![]() amitriptyline, which is a tricyclic antidepressant, or other antidepressants.People who experience frequent or severe migraine headaches may benefit from preventive medications. triptans, such as sumatriptan ( Imitrex, Tosymra) or rizatriptan (Maxalt), to block the brain’s pain signals.dihydroergotamines, in the form of a nasal spray or injection.antinausea medicines, to reduce nausea and vomiting.migraine relief medications, such as Excedrin Migraine.anti-inflammatory pain relievers, such as aspirin or ibuprofen (Advil, Motrin IB). ![]() The following over-the-counter (OTC) and prescription medicines can help treat migraine with aura: Share on Pinterest Anti-inflammatory pain relievers may help treat migraine with aura.
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